2022 MLB odds, picks, bets for Wednesday, Sept. 21 from confirmed mannequin: This four-way parlay pays nearly 18-1

September 21, 2022

Future Corridor of Famer Albert Pujols resumes his quest for profession dwelling run No. 700 when he and the St. Louis Cardinals (87-62) face the San Diego Padres (82-66) on Wednesday at Petco Park. The 42-year-old Pujols, who plans to retire after this season, has 698 profession dwelling runs, which ranks fourth all-time. Solely Barry Bonds (762), Hank Aaron (755) and Babe Ruth (714) have extra. San Diego is a -135 favourite within the newest Padres vs. Cardinals odds from Caesars Sportsbook, whereas St. Louis is a +115 underdog. The over/beneath for runs scored is 7.5.

First pitch is about for 9:40 p.m. ET from San Diego. The sport is one in every of 15 on the MLB schedule for Wednesday. Elsewhere within the majors, the Yankees slugger Aaron Decide can tie Roger Maris’ storied American League report for many dwelling runs in a season, in opposition to the Pirates, and the Guardians and White Sox sq. off in Chicago. Earlier than making any MLB picks or parlays, you should definitely see the predictions and betting recommendation from SportsLine’s confirmed laptop mannequin.

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The SportsLine Projection Mannequin simulates each MLB sport 10,000 occasions, and it’s 321-272 on top-rated MLB money-line picks for the reason that begin of the 2021 season, returning greater than $600 for $100 bettors throughout that span. This is similar mannequin that pegged the 2021 Atlanta Braves at 10-1 as one in every of three finest bets to win all of it final season. Anyone who has adopted it has seen worthwhile returns.

Now, the mannequin has locked in 4 assured MLB finest bets for Wednesday. All of them contain video games at 6:40 p.m. ET or later, so there’s nonetheless time to get these MLB picks in. Should you efficiently parlay the picks, you would be taking a look at a payout of just about 18-1. You possibly can solely see the mannequin’s MLB picks at SportsLine. 

Prime MLB picks right this moment

The mannequin, which ran 10,000 simulations on every of Wednesday’s video games, likes Kansas Metropolis (+110) to knock off Minnesota. As soon as the leaders within the AL Central, the Twins (73-75) have struggled on the highway within the second half of the season, going 5-21 of their final 26 video games away from Goal Subject. In the meantime, the Royals (59-89) have been significantly better at dwelling (35-41) than on the highway (24-48) this season.

Kansas Metropolis faces a Minnesota workforce that has struggled in September, going 6-14 in its final 20 video games. In September, the Twins have scored simply 64 runs and have an OPS of .663. Simply 4 groups have been worse in each offensive classes. See who else to again proper right here.

How you can make MLB picks and parlays for Wednesday

The mannequin additionally locked in three different finest bets for Wednesday, together with a play on an excellent larger underdog. You possibly can see the mannequin’s MLB Wednesday finest bets and parlay solely at SportsLine.

What MLB picks do you have to goal for a payout of just about 18-1? And what underdog does the mannequin like on Wednesday? Go to SportsLine now to see the MLB finest bets from a sophisticated mannequin that’s on a 321-272 run on top-rated MLB money-line picks for the reason that begin of 2021.