Learn AMA Morning Rounds®’ hottest tales in drugs and public well being from the week of Aug. 29, 2022–Sept. 2, 2022.
Ultraprocessed meals tied to elevated danger of colorectal most cancers, coronary heart illness, early dying
Ultraprocessed meals tied to elevated danger of colorectal most cancers, coronary heart illness, early dying
CNN (9/1, LaMotte) reviews, “Consuming a number of ultraprocessed meals considerably will increase males’s danger of colorectal most cancers and might result in coronary heart illness and early dying in each women and men, in accordance with two…large-scale research of individuals in the US and Italy” revealed in The BMJ. The U.S. research “examined the diets of over 200,000 women and men for as much as 28 years and located a hyperlink between ultraprocessed meals and colorectal most cancers…in males, however not ladies.” In the meantime, the Italy-based research “in contrast the position of nutrient-poor meals…versus ultraprocessed meals within the growth of persistent illness and early dying” and “discovered that each forms of meals independently elevated the danger of an early dying, particularly from cardiovascular ailments.”
FDA authorizes up to date bivalent COVID-19 vaccine boosters
The Washington Submit (8/31, McGinley) reviews, “New Omicron-targeting coronavirus booster pictures are poised for rollout after being licensed Wednesday by the Meals and Drug Administration—a transfer designed to enhance safety towards extreme sickness and dying throughout a possible rise in COVID-19 circumstances this fall and winter.” These bivalent “boosters, reformulated to take goal on the BA.4 and BA.5 Omicron subvariants dominant in the US, are scheduled to be reviewed by advisers to the” CDC and if permitted, “some boosters could also be out there beginning this weekend, with extra exhibiting up in pharmacies, [physicians’] workplaces and clinics after Labor Day.”
The AP (8/31, Neergaard) reviews, “The up to date boosters are just for individuals who have already had their major vaccinations, utilizing the unique vaccines.” The pictures “made by Pfizer and its companion BioNTech are for anybody 12 and older whereas Moderna’s up to date pictures are for adults—if it has been no less than two months since their final major vaccination or their newest booster.”
Reuters (8/31, Erman, Steenhuysen) reviews the U.S. “has secured greater than 170 million doses of the 2 pictures” for the rollout.
DEA points advisory over “brightly-colored” fentanyl drugs focusing on youth
DEA points advisory over “brightly-colored” fentanyl drugs focusing on youth
CBS Information (8/30) reviews, “The Drug Enforcement Administration issued an advisory Tuesday about an ‘rising pattern’ of ‘brightly-colored’ fentanyl drugs getting used to lure youngsters and younger folks.” The so-called “‘rainbow fentanyl’ has been seized by regulation enforcement companies in 18 states simply this month, the DEA stated.” These “medicine, made to appear to be sweet, is available in a number of kinds, together with ‘drugs, powder and blocks that resembles sidewalk chalk,’ the DEA stated.”
Statins trigger muscle ache in lower than 10% of sufferers
Statins trigger muscle ache in lower than 10% of sufferers
Based on CNN (8/29, Thomas), “for greater than 90% of sufferers on statins who expertise muscle ache, the statin is just not the reason for the ache,” in accordance with findings revealed on-line in The Lancet and offered at ESC Congress 2022. The research did discover “that within the first yr, statin remedy produced a 7% relative improve in muscle ache or weak spot, however there was no vital improve after that.” In actual fact, “the elevated danger was already current throughout the first three months after therapy was assigned.”
HealthDay (8/29, Thompson) reviews, “General, for each 1,000 folks taking a reasonable dose of statin, there have been 11 episodes of muscle ache and weak spot within the first yr, the research” authors concluded. Eugene Yang, MD, Chair of the American School of Cardiology’s Prevention of Cardiovascular Illness Council, said, “This research is in step with different research which have proven that lower than 10% of individuals have muscle-related signs like muscle aches that we are able to say appear to be related to taking a statin.”
U.S. well being officers cautiously optimistic in view of declining new monkeypox circumstances
U.S. well being officers cautiously optimistic in view of declining new monkeypox circumstances
The Washington Submit (8/26, A1, Diamond) reported that following “three months of surging monkeypox circumstances, the worldwide outbreak might have peaked, amid proof that” people are “curbing dangerous sexual behaviors and extra individuals are getting vaccinated towards a virus that unfold by shut contact.” New circumstances within the U.S. “have fallen by about 25% prior to now two weeks, from 444 circumstances a day on Aug. 10 to 337 on Aug. 24, in accordance with The Washington Submit’s rolling seven-day common.” However “whilst public well being specialists cheered the slowdown in new infections, they cautioned that the virus continues to pose a danger.”
CNBC (8/26, Kimball) reported the CDC “is cautiously optimistic that the U.S. is slowing the unfold of monkeypox as new circumstances fall in a number of main cities.”
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